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us apple developer accounts for sale:Britain advises alternative to Oxford/AstraZeneca COVID-19 vaccine for under-30s


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LONDON - Britain should give an alternative to Oxford/AstraZeneca's COVID-19 vaccine to under 30s where possible due to a "vanishingly" rare side effect of blood clots in the brain, Britain's vaccine advisory committee said on Wednesday.

Officials said the benefits of the shot continued to outweigh its risks for the vast majority, after safety concerns spurred over a dozen countries in recent weeks to suspend use of the vaccine following reports linking it to a brain blood clotting disorder. Britain has kept using the shot throughout.

Wei Shen Lim, chair of Britain's Joint Committee on Vaccination and Immunisation (JCVI), said that based on the available data and evidence, it was preferable for adults aged under 30 with no underlying conditions to be offered an alternative to the AstraZeneca vaccine where available.

He said that for younger people, where the risks of hospitalisation were much lower, the risk/benefit calculation of the Oxford/AstraZeneca shot meant others vaccines were preferable.

"We are advising a preference for one vaccine over another vaccine for a particular age group, really out of the utmost caution, rather than because we have any serious safety concerns," Lim said at a briefing.

He said people should continue to have a second dose of the AstraZeneca shot if they had received a first dose.

June Raine, chief executive of the UK's MHRA medicine regulator, said that over 20 million AstraZeneca vaccine doses had been given by March 31, with 79 case reports of the side effect and 19 deaths, all after first doses of the shot.

"This is a vanishingly rare, but sadly quite serious, adverse event..., and you can't pick these kind of things up until you have literally deployed tens of millions of doses of vaccine," Deputy Chief Medical Officer Jonathan Van-Tam said.

He added that the move would have only a negligible impact on the pace of Britain's vaccine rollout.

The rollout of Moderna's shot began on Wednesday, while Britain is also deploying Pfizer's vaccine, and Prime Minister Boris Johnson said the move on AstraZeneca would not impact England's roadmap out of lockdown.

"As the regulators have said, this vaccine is safe, effective and has already saved thousands of lives - and the vast majority of people should continue to take it when offered," he said.


The change to advice on Britain's vaccine rollout came after its MHRA medicine regulator said the reports of rare brain blood clotting were a suspected side-effect from the COVID-19 vaccine developed by Oxford University and AstraZeneca.

MHRA chief Raine said the benefits of the shot outweighed the risks for the vast majority, echoing an update from Europe's medicine regulator also made on Wednesday.


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